The slave ship Saint Luc left the African coast carrying enslaved Africans toward Haiti. About 131 people had been taken aboard.

Vessel: Saint Luc; flag: France; estimated standardized tonnage: 146.3. People recorded in connection with the voyage: Investor: Schiell, Luc; Captain: Hélie, Jean. The voyage began at Nantes on 6 July 1721. Principal recorded place where captives were acquired: Windward + Ivory + Gold + Benin (Other Africa). Principal recorded disembarkation place: Cap Français. Recorded duration of the captives' Atlantic crossing: 100 days. Estimated mortality during the crossing: 21.0%. Recorded outcome: Shipwrecked or destroyed - unspecified.