The slave ship Isabel left the African coast carrying enslaved Africans toward Brazil. About 490 people had been taken aboard.

Vessel: Isabel; flag: Portugal / Brazil; rig: Brig; estimated standardized tonnage: 172. People recorded in connection with the voyage: Investor: Souza, Jorge José de; Captain: Santos, Joaquim Correa dos. The voyage began at Rio de Janeiro on 5 November 1846. Principal recorded place where captives were acquired: Luanda (West Central Africa and St Helena). Principal recorded disembarkation place: Rio de Janeiro. Recorded outcome: Arrived in Africa, subsequent fate unknown.