The slave ship Leão departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Brazil.

Vessel: Leão; flag: Portugal / Brazil; rig: Brig; estimated standardized tonnage: 218. People recorded in connection with the voyage: Investor: Silva, João Antônio Alves da; Captain: Melo, José Joaquim Pereira de. The voyage began at Pernambuco, place unspecified on 11 February 1845. Principal recorded place where captives were acquired: Luanda (West Central Africa and St Helena). Principal recorded disembarkation place: Pernambuco, place unspecified. Recorded outcome: Arrived in Africa, subsequent fate unknown.