The slave ship Orphee left the African coast carrying enslaved Africans toward Cuba. About 698 people had been taken aboard.

Vessel: Orphee; flag: France; rig: Ship; estimated standardized tonnage: 435. People recorded in connection with the voyage: Captain: Coquard; Investor: François. The voyage began at Santiago de Cuba on 15 May 1825. Principal recorded place where captives were acquired: Calabar (Bight of Biafra and Gulf of Guinea islands). Principal recorded disembarkation place: Santiago de Cuba. Estimated mortality during the crossing: 6.9%. Recorded outcome: Voyage completed as intended.