The slave ship Polifemo departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Brazil.

Vessel: Polifemo; flag: Portugal / Brazil; rig: Bergantim. People recorded in connection with the voyage: Captain: Santos, Antônio Teodoro dos; Investor: Souza, Domingos de Carvalho e. The voyage began at Rio de Janeiro on 25 April 1822. Principal recorded place where captives were acquired: Cabinda (West Central Africa and St Helena). Principal recorded disembarkation place: Rio de Janeiro. Recorded duration of the captives' Atlantic crossing: 28 days. Estimated mortality during the crossing: 1.0%. Recorded outcome: Voyage completed as intended.