The slave ship General Rêgo arrived with enslaved Africans in Brazil. About 510 people had been taken aboard and approximately 452 arrived.

Vessel: General Rêgo; flag: Portugal / Brazil; rig: Bergantim. People recorded in connection with the voyage: Captain: Alcântara, Marcelino José de; Investor: Alcântara, Marcelino José de; Captain: Pena, José Antônio. The voyage began at Rio de Janeiro on 23 January 1821. Principal recorded place where captives were acquired: Luanda (West Central Africa and St Helena). Principal recorded disembarkation place: Rio de Janeiro. Recorded duration of the captives' Atlantic crossing: 36 days. Estimated mortality during the crossing: 11.0%. Recorded outcome: Voyage completed as intended.