The slave ship Polifemo left the African coast carrying enslaved Africans toward Brazil. About 394 people had been taken aboard.

Vessel: Polifemo; flag: Portugal / Brazil; rig: Bergantim. People recorded in connection with the voyage: Investor: Carvalho, Manoel Gonçalves de; Captain: Pedrosa, Manoel Carvalho; Investor: Pedrosa, Manoel Carvalho. The voyage began at Rio de Janeiro on 16 May 1821. Principal recorded place where captives were acquired: Mozambique (East Africa and Indian Ocean islands). Principal recorded disembarkation place: Rio de Janeiro. Recorded duration of the captives' Atlantic crossing: 54 days. Recorded outcome: Voyage completed as intended.