The slave ship Espoir departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Cuba.

Vessel: Espoir; flag: France; rig: Schooner; estimated standardized tonnage: 109. People recorded in connection with the voyage: Investor: Dennis, Pierre-Thomas; Captain: Sempreur Lempereur; Captain: Leray, Emile; Investor: Dutaux. The voyage began at Nantes on 11 July 1821. Principal recorded place where captives were acquired: Gallinhas (Sierra Leone). Principal recorded disembarkation place: Santiago de Cuba. Estimated mortality during the crossing: 0.5%. Recorded outcome: Returned direct to Africa after bringing enslaved people to the Americas.