The slave ship Dois Amigos departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Brazil.

Vessel: Dois Amigos; flag: Portugal / Brazil; rig: Schooner. People recorded in connection with the voyage: Investor: Novaes, Caetano Raimundo de; Captain: Santos, Manoel Rodrigues dos; Investor: Santos, Manoel Rodrigues dos. The voyage began at Pernambuco, place unspecified on 16 September 1818. Principal recorded place where captives were acquired: São Tomé or Princes Island (Bight of Biafra and Gulf of Guinea islands). Principal recorded disembarkation place: Pernambuco, place unspecified. Recorded outcome: Left home port, no further record.