The slave ship Isaac departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Guadeloupe.

Vessel: Isaac; flag: Great Britain; rig: Sloop; estimated standardized tonnage: 46. People recorded in connection with the voyage: Investor: Hayes, Thomas; Investor: Newton, Samuel; Investor: Graham, Thomas; Captain: Byass, William. The voyage began at Liverpool on 28 July 1806. Principal recorded place where captives were acquired: Windward Coast (Nunez - Assini) (Other Africa). Principal recorded disembarkation place: Basse-Terre. Recorded outcome: Captured by the French - after embarkation of enslaved people.