The slave ship Constance departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Antigua and Barbuda.

Vessel: Constance; flag: Great Britain; rig: Brig; estimated standardized tonnage: 168. People recorded in connection with the voyage: Investor: Case, George; Captain: Tittle, Thomas; Captain: Laffer, Henry. The voyage began at Liverpool on 18 March 1806. Principal recorded place where captives were acquired: Calabar (Bight of Biafra and Gulf of Guinea islands). Principal recorded disembarkation place: Saint John (Antigua). Recorded outcome: Voyage completed as intended.