The slave ship William and Mary departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Guyana.

Vessel: William and Mary; flag: Great Britain; rig: Brig; estimated standardized tonnage: 70. People recorded in connection with the voyage: Investor: Hayes, Thomas; Captain: Bird, Adam; Investor: Bird, Adam; Captain: Reid. The voyage began at Liverpool on 16 September 1804. Principal recorded place where captives were acquired: Windward Coast (Nunez - Assini) (Other Africa). Principal recorded disembarkation place: Demerara. Recorded outcome: Voyage completed as intended.