The slave ship Isabella departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Dominica.

Vessel: Isabella; flag: Great Britain; rig: Ship; estimated standardized tonnage: 102. People recorded in connection with the voyage: Captain: Lyttleton, William; Investor: Lyttleton, William; Captain: Taylor, Robert. The voyage began at London on 18 November 1791. Principal recorded place where captives were acquired: Gambia (Senegambia and offshore Atlantic). Principal recorded disembarkation place: Dominica, place unspecified. Recorded outcome: Returned direct to Africa after bringing enslaved people to the Americas.