The slave ship Santana e S Domingos left the African coast carrying enslaved Africans toward Brazil. About 427 people had been taken aboard.

Vessel: Santana e S Domingos; flag: Portugal / Brazil; rig: Galera. People recorded in connection with the voyage: Captain: Vieira, Manoel Ferreira; Investor: Silva, Domingos Dias da; Investor: Bandeira, José Álvares. The voyage began at Lisbon on 23 July 1765. Principal recorded place where captives were acquired: Luanda (West Central Africa and St Helena). Principal recorded disembarkation place: Rio de Janeiro. Recorded outcome: Bought at least one slave in Africa - subsequent fate unknown.