The slave ship Two Sisters departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Jamaica.

Vessel: Two Sisters; flag: Great Britain; rig: Snauw; estimated standardized tonnage: 146.3. People recorded in connection with the voyage: Captain: Webb, Samuel; Investor: Webb, Samuel; Captain: Cowie, Robert. The voyage began at Bristol on 16 May 1754. Principal recorded place where captives were acquired: New Calabar (Bight of Biafra and Gulf of Guinea islands). Principal recorded disembarkation place: Kingston. Recorded outcome: Voyage completed as intended.