The slave ship Seine left the African coast carrying enslaved Africans toward Haiti. About 609 people had been taken aboard.

Vessel: Seine; flag: France; estimated standardized tonnage: 321.1. People recorded in connection with the voyage: Captain: Laragon, Thomas; Investor: Michel; Investor: Grou. The voyage began at Nantes on 9 December 1751. Principal recorded place where captives were acquired: Whydah, Ouidah (Bight of Benin). Principal recorded disembarkation place: Léogane. Recorded duration of the captives' Atlantic crossing: 110 days. Estimated mortality during the crossing: 4.0%. Recorded outcome: Voyage completed as intended.