The slave ship NS da Guia e S Boaventura departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Brazil.

Vessel: NS da Guia e S Boaventura; flag: Portugal / Brazil; rig: Patacho. People recorded in connection with the voyage: Captain: Cruz, Domingos Rodrigues; Investor: Cruz, Domingos Rodrigues; Investor: Álvares, Antônio Afonso. The voyage began at Bahia, place unspecified on 13 May 1721. Principal recorded place where captives were acquired: Costa da Mina, place unspecified (Bight of Benin). Principal recorded disembarkation place: Bahia, place unspecified. Recorded outcome: Left home port, no further record.