The slave ship Isabel departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Brazil.

Vessel: Isabel; flag: Portugal / Brazil; rig: Brig; estimated standardized tonnage: 172. People recorded in connection with the voyage: Investor: Souza, Jorge José de; Captain: Santos, Joaquim Correa dos. The voyage began at Rio de Janeiro on 5 November 1846. Principal recorded place where captives were acquired: Luanda (West Central Africa and St Helena). Principal recorded disembarkation place: Rio de Janeiro. Recorded outcome: Arrived in Africa, subsequent fate unknown.