The slave ship NS da Guia arrived with enslaved Africans in Brazil. About 529 people had been taken aboard and approximately 436 arrived.

Vessel: NS da Guia; flag: Portugal / Brazil; rig: Brig. People recorded in connection with the voyage: Investor: Cirne, Manoel Joaquim Mendes de Vasconcelos; Captain: Silva, José Jorge da; Investor: Silva, José Jorge da. The voyage began at Rio de Janeiro on 14 June 1821. Principal recorded place where captives were acquired: Quilimane (East Africa and Indian Ocean islands). Principal recorded disembarkation place: Rio de Janeiro. Recorded duration of the captives' Atlantic crossing: 81 days. Estimated mortality during the crossing: 18.0%. Recorded outcome: Voyage completed as intended.