The slave ship Fame left the African coast carrying enslaved Africans toward Guyana. About 338 people had been taken aboard.

Vessel: Fame; flag: Great Britain; rig: Ship; estimated standardized tonnage: 396. People recorded in connection with the voyage: Investor: Neilson, William; Investor: Heathcoat, William; Captain: Davidson, Richard. The voyage began at Liverpool on 16 November 1803. Principal recorded place where captives were acquired: Sierra Leone estuary. Principal recorded disembarkation place: Demerara. Estimated mortality during the crossing: 7.0%. Recorded outcome: Voyage completed as intended.