The slave ship William and Margaret departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Saint Barthélemy.

Vessel: William and Margaret; flag: U.S.A.; rig: Schooner; estimated standardized tonnage: 95. People recorded in connection with the voyage: Captain: Read, John (Jr); Investor: Dennis, Thom; Captain: Soubiron, Meinhard. The voyage began at Rhode Island, port unspecified on 16 December 1799. Principal recorded place where captives were acquired: Africa, port unspecified (Other Africa). Principal recorded disembarkation place: Gustavia, St Barthélemy. Estimated mortality during the crossing: 67.0%. Recorded outcome: Condemned - Americas after disembarkation.