The slave ship James and Francis departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Jamaica.

Vessel: James and Francis; flag: Great Britain. People recorded in connection with the voyage: Investor: Matthews, Jonathan; Captain: Edwards, Thomas; Investor: Gracedieu, Bartholomew; Investor: Walthall, Hanbury; Investor: Loyd, John. The voyage began at London on 9 February 1699. Principal recorded place where captives were acquired: Bonny (Bight of Biafra and Gulf of Guinea islands). Principal recorded disembarkation place: Jamaica, place unspecified. Estimated mortality during the crossing: 64.0%.