The slave ship Preston departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Antigua and Barbuda.

Vessel: Preston; flag: Great Britain; rig: Brig; estimated standardized tonnage: 182.3. People recorded in connection with the voyage: Investor: Earle, Thomas; Captain: Earle, William; Investor: Earle, William; Investor: Heywood, Benj Arth; Investor: Parke, Thomas; Captain: Copeland, Jno; Investor: Copeland, Jno; Investor: Davenport, William; Investor: Earle, William (Jr); Captain: Brighouse, William. The voyage began at Liverpool on 20 August 1781. Principal recorded place where captives were acquired: Cameroons (Bight of Biafra and Gulf of Guinea islands). Principal recorded disembarkation place: Saint John (Antigua). Recorded outcome: Voyage completed as intended.