The slave ship Prins Willem de Vijfde departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Sint Eustatius.

Vessel: Prins Willem de Vijfde; flag: Netherlands; rig: Fregat; estimated standardized tonnage: 316. People recorded in connection with the voyage: Captain: Loef, Cornelis; Investor: Middelburgsche Commercie Compagnie. The voyage began at Vlissingen on 27 June 1771. Principal recorded place where captives were acquired: Malembo (West Central Africa and St Helena). Principal recorded disembarkation place: St Eustatius. Estimated mortality during the crossing: 1.0%. Recorded outcome: Sold.