The slave ship Prins Willem de Vijfde departed on a transatlantic slave-trading voyage that would carry enslaved Africans to Sint Eustatius.

Vessel: Prins Willem de Vijfde; flag: Netherlands; rig: Fregat; estimated standardized tonnage: 288. People recorded in connection with the voyage: Captain: Jacobs, A; Investor: Middelburgsche Commercie Compagnie. The voyage began at Zeeland on 9 March 1761. Principal recorded place where captives were acquired: Cape Lahou (Windward Coast). Principal recorded disembarkation place: St Eustatius. Recorded duration of the captives' Atlantic crossing: 58 days. Estimated mortality during the crossing: 4.0%. Recorded resistance: Insurrection planned, but thwarted. Recorded outcome: Voyage completed as intended.