The slave ship Hesketh left the African coast carrying enslaved Africans toward Jamaica. About 269 people had been taken aboard.

Vessel: Hesketh; flag: Great Britain; rig: Snauw; estimated standardized tonnage: 164.3. People recorded in connection with the voyage: Captain: Copeland, Jno; Investor: Copeland, Jno; Captain: Nicholas, Rd; Investor: Nicholas, Rd; Investor: Williamson, John; Investor: Rowe, William; Investor: Falkner, Thomas; Investor: Clowes, George. The voyage began at Liverpool on 21 September 1754. Principal recorded place where captives were acquired: Gold Coast, port unspecified. Principal recorded disembarkation place: Kingston. Estimated mortality during the crossing: 38.7%. Recorded outcome: Voyage completed as intended.