The slave ship Louise Marguerite left the African coast carrying enslaved Africans toward Haiti. About 340 people had been taken aboard.

Vessel: Louise Marguerite; flag: France; estimated standardized tonnage: 343.1. People recorded in connection with the voyage: Captain: Fessard, Étienne; Investor: Struyckman, Conrard; Investor: Struyckman, Jean. The voyage began at Nantes on 23 November 1749. Principal recorded place where captives were acquired: Whydah, Ouidah (Bight of Benin). Principal recorded disembarkation place: Léogane. Recorded duration of the captives' Atlantic crossing: 206 days. Estimated mortality during the crossing: 83.0%. Recorded resistance: Revolt by enslaved people. Recorded outcome: Voyage completed as intended.